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A
deficiency of progesterone can explain most of symptoms of menopause.
Hot flashes are a response to withdrawal from estrogen and progesterone.
Progesterone levels fall, because women no longer ovulate after
menopause. Estrogen levels do not fall in balance with progesterone,
because women are exposed to
estrogen from other sources outside the ovary. Adding progesterone
restores balance and safely relieves symptoms. Adding more estrogen
may relieve hot flashes, but it increases the imbalance and causes
side effects which include bleeding, weight gain, stroke, and
increased risk of breast cancer, etc.
Mood swings can also be traced to progesterone deficiency or an
estrogen excess. Progesterone has a calming sedative effect on
the brain. It attaches to a receptor in the brain that decreases
anxiety and elevates mood. This receptor in the brain is called
the GABA receptor. This same GABA receptor allows antidepressants
and anti-anxiety drugs to produce their
effect on the brain. Menopausal women on antidepressants may benefit
from the antidepressant effects of progesterone which could eliminate
the need for antidepressants.
Insomnia is another frequent complaint of women during menopause.
Insomnia in this case is probably due to the lack of the calming
effects of progesterone. Replacing progesterone usually improves
insomnia.
Many women complain of poor concentration and lapses in memory
during menopause. Progesterone is involved with providing insulation
to nerve cells. Myelin is like rubber around electrical wires.
Myelin insulates nerve cells and improves conduction of nerve
impulses. Decreased progesterone may interrupt the production
of myelin and interfere with brain impulses.
Estrogen without the proper amount of progesterone can interfere
with thyroid hormone function. Thyroid hormone is necessary to
properly metabolize food and convert it into energy. If thyroid
hormone is not functioning properly, women experience weight gain,
fatigue, food cravings, and symptoms of low blood sugar.
Other disturbing symptoms include the loss of scalp hair and the
growth of facial hair after menopause. Testosterone, the male
hormone, can be produced by the ovary and the adrenal gland after
menopause. The body uses testosterone to balance estrogen in the
absence of progesterone. This results in male pattern baldness
and facial hair growth. Replacing progesterone usually reverses
the process, thereby initiating growth of scalp hair and
stopping facial hair growth.
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Do
I Need Estrogen?
Menopause
cannot be simply explained by lack of estrogen. While estrogen
deficiency may play a role in some women’s experiences,
in most cases it does not. The key to minimizing menopausal
symptoms is a balance between estrogen and progesterone.
Most women
in America are over their ideal body weight. It is well documented
that overweight women produce to too much estrogen. Estrogen
is made in fat cells. Women who are overweight are at an increased
risk of diseases that are known to be caused by elevated estrogen.
Uterine cancer and breast cancer are more common in women who
are overweight.
Estrogen
also increases weight gain and makes it more
difficult to lose weight. Women, who are overweight should not
take standard estrogen replacement unless a saliva test indicates
an imbalance.
Women who are not at risk for osteoporosis should not take estrogen
replacement. Estrogen has two FDAapproved indications. One is
the relief of hot flashes, the other is the prevention of osteoporosis
in women who are at high risk. However, we contend that no one
should take estrogen with out salivary testing. Studies show
that weight-bearing exercise decreases bone loss more than estrogen.
If a woman is experiencing hot
flashes,restoring balance with progesterone can alleviate the
symptoms, if saliva testing indicates a
progesterone deficiency.
Also, using weaker estrogens, like estriol or the estrogens
found in soy, can restore balance by blocking the effect of
stronger estrogens.
Not all women
are at high risk for osteoporosis. Women of North European decent
with a thin frame, sedentary lifestyle, history of smoking,
and prolonged steroid use are at risk for osteoporosis. Women
not in this high-risk group do not need estrogen bone to maintain
normal bone health.
People
of color are at very low risk for osteoporosis
and should not take estrogen for osteoporosis prevention. Although
in some cases very thin fair-skinned women of color may be at
risk.
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